Autoridades

Email: 
carmen.pizarro@usach.cl
Secretaria: Sra. Patricia Jara A
Mail: patricia.jara.a@usach.cl
Teléfono: 
27 181 006
Email: 
decanafqb@usach.cl
Descripción: 

Secretaria: Sra. Patricia Jara A.Mail: patricia.jara.a@usach.clTel: (56-02) 27 181 006

Email: 
bernardo.morales@usach.cl
Teléfono: 
27 181 002
Sitio web: 
Elsevier
Research
Our work is focused on plastic modifications of neuronal circuits in the hippocampus, prefrontal cortex and visual cortex using sensory experiments, cognitive processes and natural and artificial neuromodulators. Long Term Potentiation (LTP) and Long Term Depression (LTD) are used as models to understand synaptic modifications underlying higher cognitive phenomena such as learning and memory.
Línea(s) de investigación: 
Memoria y Aprendizaje
Jerarquía: 
Titular
Grados académicos /educación: 
Doctor en Ciencias, mención Biología Molecular, Celular y Neurociencias, Facultad de Ciencias, Universidad de Chile
Biólogo Marino, Universidad de Concepción, 1984
Email: 
carmen.pizarro@usach.cl
Teléfono: 
227 181 004

Abstract

The research interest involves physical and chemical characterization of soil minerals, particularly with Mössbauer spectroscopy, and uses of iron oxides-containing materials as heterogeneous catalysts for environmental remediation.

Línea(s) de investigación: 
Físico química de suelos y medio ambiente
Jerarquía: 
Titular
Grados académicos /educación: 
Doctor en Química, Universidad de Santiago de Chile. 2001
Químico, Universidad de Santiago de Chile.
Email: 
iriux.almodovar@usach.cl
Teléfono: 
27 181 161
Sitio web: 
http://www.experts.scival.com/UdeSantiago/expert.asp?n=IRIUX%20ALMODOVAR%20FAJAR…

Abstract

Developing of green synthetic strategies to obtain compounds with interesting pharmacological properties.

Línea(s) de investigación: 
Síntesis Orgánica - Mecanismos de reacción, Química Verde
Jerarquía: 
Asistente
Grados académicos /educación: 
Químico, Universidad de La Habana, 1996
Doctor en Química, Universidad de Chile, 2006.
Publicaciones: 

  • Jorge Ariel Saavedra-Olavarría*, Patricio Hermosilla-Ibáñez, Edwin G. Pérez, and Iriux Almodóvar (2022), “Fast Heating-Assisted One-pot Copper-Catalysed Sulfonylation and Sulfochlorination of Styrenes” Eur. J. Org. Chem. 2022, e202101526. (IF=3,021)

  • Arteaga, Gean C.; Saavedra-Olavarria, Jorge; Almendras, Sebastian; Hermosilla-Ibanez, Patricio; Almodovar, Iriux; Perez, Edwin G.* Copper-catalyzed intermolecular aminochlorination of alkenes. Tetrahedron Letters, 2018, 59, (12),191-193 (IF=2.415)

  • Saavedra-Olavarria, Jorge; Madrid-Rojas, Matias; Almodovar, Iriux; Hermosilla-Ibanez, Patricio; Perez, Edwin G*. Synthesis of beta-alkoxy-N-protected phenethylamines via one-pot copper-catalyzed aziridination and ring opening. RSC Advances, 2018, 8, (49), 27919-27923 (IF=3.390)

  • Almodovar, Iriux*; Caroli Rezende, Marcos; Cassels, Bruce K.; Garcia-Arriagada, Macarena, Theoretical insights into the regioselectivity of a Pictet-Spengler reaction: Transition state structures leading to salsolinol and isosalsolinol, JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, 2017, 30 (8) (IF=2.391)

  • C. Aliaga, I. Almodovar and M. C. Rezende, A single theoretical descriptor for the bond-dissociation energy of substituted phenols, J. Mol. Model., 21 (2015), 2572. Impact Factor=1.867I.

  • M. C. Rezende, I. Ponce, R. Oñate, I. Almodovar, C. Aliaga. Change of mechanism with a change of substituents for a Zincke reaction. Tetrahedron Letters 55 (2014) 3097. Impact Factor= 2.397.

  • P. Abarca, P. Silva, I. Almodovar, M. C. Rezende* Preparation and properties of perichromic dye: an undergraduate laboratory, Quim. Nova, 37(4) (2014) 745. Impact Factor =0.737.

  • I. Almodovar*, T. Delgado-Castro, G. Zapata-Torres, M. C Rezende, R. Araya-Maturana, Factors affecting the competitive reduction of 8,8-dimethylnaphthalene-1,4,5(8H)-trione in a Diels-Alder cycloaddition with hydroxysulfinyldienes. J.Iran.Chem.Soc., (2014), Volume 11, Issue 4, 1021-1026 . Impact Factor= 1.467.

  • I. Almodovar*, W. Cardona, T. Delgado-Castro, G. Zapata-Torres, M. C. Rezende, R. Araya-Maturana, M. C. Maestro, J. L. García Ruano, Remote regio- and stereocontrol by the sulfinyl group. Diels-Alder reaction of sulfinyl dienols and 8,8-dimethylnaphthalene-1,4,5(8H)-trione. Tetrahedron: Asymmetry, 24 (2013) 56. Impact Factor= 2.652.

  • M. A. Juricic*, P. A. Berríos-Cárcamo, M. L. Acevedo, Y. Israel, I. Almodovar, B. K. Cassels, Salsolinol and isosalsolinol: condensation products of acetaldehyde and dopamine.Separation of their enantiomers in the presence of a large excess of dopamine. Journal of pharmaceutical and biomedical analysis, 63 (2012) 170. Impact Factor=2.723.

  • M. C. Rezende*, I. Almodovar, Substituent electrophilicities in the NMR spectra of barbituric Derivatives, Magnetic Resonance in Chemistry, 50 (2012) 266. IF= 1,247.

  • H. Pessoa-Mahana*, I. M. Cuevas, D. C. Pessoa-Mahana, R. Araya-Maturana, I. Almodovar and C. A. Saitz-Barrá, Synthesis of 1-Benzyl-3-[4-(Aryl-1-Piperazinyl) Carbonyl]-1h-Indoles: Novel Ligands With Potential D4 Dopaminergic Activity. Journal of Chilean Chemical Society, 56, 4 (2011) 866. Impact Factor= 0.448.

  • I. Almodovar*, O. Ramírez-Rodríguez, A. Barriga, M. C. Rezende, R. Araya-Maturana, Electrospray ionization mass spectrometric fragmentation of hydroquinone derivatives. Rapid Commun. Mass Spectrom. 25 (2) (2011) 370. Impact Factor=2.846.

Capítulo de Libro:

Sandra Patricia Rojas Rojas , Iriux Almodovar, Ignacio Tapia, Nicolás Troncoso and David Leal,” “Promoción de habilidades de pensamiento científico y el diagrama heurístico en las actividades de laboratorio de Química Orgánica I. Experiencia en la formación de futuros profesores de química y biología.” Innovar y Transformar desde las Disciplinas: Experiencias claves en la Educación Superior en América Latina y El Caribe 2021-2022 https://doi.org/10.34720/zmdk-a274

Proyectos: 
No1211619 ,Co-investigadora,  (ANID 2021-2025)

No 018-2018, Investigadora Principal  (PID, VRA Marzo 2019- Agosto 2020)

No 012-2018, Co-investigadora  (PID, VRA, Marzo 2019- Agosto 2020)

No 1171391, Co-investigadora (FONDECYT 2017-2021)

021641AF, Investigadora responsable (DICYT 2016-2019)

Nº 11121270 (Iniciación).  Investigadora Principal. 2012 - 2015.

 
Nº 3100059 (Postdoctorado). Investigadora Principal. 2009 - 2012.
Email: 
gloria.levican@usach.cl
Teléfono: 
27 181 125
Sitio web: 
http://www.experts.scival.com/UdeSantiago/expert.asp?n=CLAUDIO%20A%20LAURIDO%20F…

Our research is focused on the elucidation of the molecular elements involved in adaptation of microorganisms to environmental changes. We are especially interested in characterization of the oxidative stress response of acidophilic bioleaching bacteria used in the recovery of metals from sulfide ores.  These microorganisms are a suitable model to study this response because of they are exposed to very highly oxidative conditions such as very acid pH and extremely high metal concentration.

Línea(s) de investigación: 
Ecofisiología bacteriana, estrés oxidativo en bacterias biolixiviantes, extremófilos. Biotecnología.
Jerarquía: 
Asociado
Grados académicos /educación: 
Doctor (Ph.D) en Cs. Biológicas mención Microbiología. Universidad de Chile, 2003
Licenciada en Cs. Biológicas
Publicaciones: 
  1. Contreras M, Mascayano C, Chávez R, Ferrer A, Paillavil B, Levicán G. (2015). Dyp-Type Peroxidase (DypA) from the Bioleaching Acidophilic Bacterium Leptospirillum ferriphilum DSM 14647. Advanced Materials Research 1130: 23-27. 
  2. Gil-Durán C, Rojas-Aedo JF, Medina E, Vaca I, García-Rico RO, Villagrán S, Levicán G, Chávez R. The pcz1 Gene, which Encodes a Zn(II)2Cys6 Protein, Is Involved in the Control of Growth, Conidiation, and Conidial Germination in the Filamentous Fungus Penicillium roqueforti. PLoS One. (2015) Mar 26;10(3):e0120740. doi: 10.1371/journal.pone.0120740. eCollection 2015.
  3. Farah C, Levicán G, Ibba M, Orellana O. Effect of hydrogen peroxide on the biosynthesis of heme and proteins: potential implications for the partitioning of GlutRNA(Glu) between these pathways. Int J Mol Sci. (2014) Dec 11;15(12):23011-23. doi: 10.3390/ijms151223011.
  4. Valdés N, Rivera-Araya J, Bijman J, Escudero L, Demergasso C, Fernández S, Ferrer A, Chávez R, Levicán G. Draft Genome Sequence of Nitrincola sp. Strain AD6, an Arsenic-Resistant Gammaproteobacterium Isolated from a Salt Flat. Genome Announc. (2014) Nov 20;2(6). pii: e01144-14. doi:10.1128/genomeA.01144-14.
  5. Del-Cid A, Ubilla P, Ravanal MC, Medina E, Vaca I, Levicán G, Eyzaguirre J, Chávez R. Cold-active xylanase produced by fungi associated with Antarctic marine sponges. Appl Biochem Biotechnol. (2014) Jan;172(1):524-32. doi: 10.1007/s12010-013-0551-1.
  6. Eherenfeld N, Levicán G, Parada P. (2013). Heterodisulfide reductase from Acidithiobacilli is a key component involved in metabolism of reduced inorganic sulfur compounds. Adv. Mat. Res., 825: 194-197.
  7. Bustamante P, Covarrubias O, Levicán G, Katz A, Tapia P, Holmes D, Quatrini R, Orellana O. (2012). ICEAfe1, an actively excising genetic element from the biomining bacterium Acidithiobacillus ferrooxidans. Journal of Molecular Microbiology and Biotechnology (Enviada).
  8. Cárdenas JP, Moya F, Covarrubias P, Shmaryahu A, Demergasso C, Levicán G, Holmes DS, Quatrini R. (2012). Comparative genomics of the oxidative stress response in bioleaching microorganisms. Hydrometallurgy 127–128: 162–167
  9. Norambuena J, Flores R, Cárdenas JP, Quatrini R, Chávez, R, Levicán G. (2012) Thiol/Disulfide system plays a crucial role in redox protection in the acidophilic iron-oxidizing bacterium Leptospirillum ferriphilum. Plos One 7(9):e44576.
  10. Levicán G, Gómez, MJ, Chávez, R, Orellana, O, Moreno-Paz, M, Parro, V. J. (2012). Comparative genomic analysis reveals novel facts in the cytochromes of Leptospirillum spp. Levicán, G. J Mol Microbiol Biotechnol., 22: 94-104.
  11. Vaca I, Faúndez C, Maza F, Paillavil B, Hernández V, Acosta F, Levicán G, Martínez C, Chávez R. (2012). Cultivable psychrotolerant yeasts associated with Antarctic marine sponges. World J Microbiol Biotechnol (Publicada)
  12. Ravanal, M.C., Espinosa, Y., Rosa, L., Vaca, I., Polanco, R., Eyzaguirre, J., Levicán, G, Chavez, R. (2012). Glucose-induced production of a Penicillium purpurogenum xylanase by Aspergillus nidulans. Mycoscience, 53: 152-155.
  13. De Armas M, Levicán G, Katz A, Moser J, Jahn D, Orellana O. (2011). Cellular levels of heme affect the activity of dimeric glutamyl-tRNA reductase. Biochem. Biophys. Res. Com., 405: 134-139.
  14. Espinosa Y., Trebotich J., Sepúlveda F., Cadena J., Vargas-Straube M.J., Vaca I., Bull P., Levicán G., Chávez R. (2011). Production of a heterologus recombinant protein using fragments of the glyceraldehyde-3-phosphate dehydrogenase promoter from Penicillium camemberti. World J. Microbiol. Biotechnol. 27: 3019-3023.
  15. Badilla Fazzini RA, Levicán G, Parada P. (2011). Acidithiobacillus thiooxidans secretome containing a newly described lipoprotein Licanantase enhances chalcopyrite bioleaching rate. App. Microbiol. Biotechnol., 89: 771-780.
  16. De Armas-Ricard M, Levicán G, Katz A, Moser J, Jahn D, Orellana O. (2011). Cellular levels of heme affect the activity of dimeric glutamyl-tRNA reductase. Biochem. Biophys. Res. Com., 405: 134- 139.
 
Proyectos: 
  • Fondecyt Iniciación 1085045 3 años 2009-2011 IR
  • Fondecyt Regular 1110203 4 años 2010-2014 CI
  • Fondecyt Regular 1120746 4 años 2012-1015 IR
  • Fondecyt Regular 1150834 4 años 2015-2018 CI