Caroli Rezende Marcos

Email: 
marcos.caroli@usach.cl
Teléfono: 
27 181 035
Sitio web: 
Sitio web

Research Interests

Studied subjects are:

  • Solvato and halochromic dyes: synthesis, spectral and theoretical studies on their behaviour in solution
  • Mechanisms of organic reactions in solution.
  • Structure-activity relationships in bio-organic systems.
Jerarquía: 
Titular
Línea de investigación: 
Química Orgánica, Físico-Química Orgánica
Grados académicos /educación: 
Químico, Universidad Federal de Rio de Janeiro.
Doctor en Química, Universidad de East Anglia, Inglaterra. 1980
Publicaciones: 

1. “ A Two-step Method for the Preparation of Chiral Cathinones”, M. Osorio-Olivares, M. C. Rezende *, S. Sepúlveda-Boza,  B. K.Cassels, R. F. Baggio  and J. C. Muñoz-Acevedo, Tetrahedron: Asymmetry, 2003, 14, 1473-1477.

2. “Solute-Solvent Interactions of Flavonoids in Organic Solvents”, C. Sandoval, M.C.Rezende* and F. González-Nilo, J.Sol.Chem., 2003 , 32,  781-790.

3. “An NMR Study of Merocyanine-type Dyes Derived from Barbituric Acid”, P.Flores, M.C.Rezende *, L. Villarroel and J. Guerrero, Spectrochim.Acta Part A, 2004,  60, 1637-1640

4. “A Solvatochromic Derivative of Meldrum’s Acid”, P. Flores, M.C.Rezende * and F. Jara, Dyes and Pigments, 2004, 62, 277-281.

5. “1-Benzyl-1,2,3,4-Tetrahydroisoquinolines  1H NMR conformational Studies and Rotational Barriers”, P. Iturriaga-Vásquez *, G. Zapata-Torres, M.C.Rezende and B.K.Cassels, J.Chil.Chem.Soc., 2004, 49, 17-23.

6. “MAO Inhibition by Arylisopropylamines: the Effect of Oxygen Substituents at the b-Position”,M. Osorio-Olivares, M. C. Rezende *, S. Sepúlveda-Boza, B. K. Cassels, and A. Fierro, Bioorg. Med.Chem., 2004 , 12 , 4055-4066.   

7. “Relative solvation and strength of polycyano- and polynitro-methanes in water: a study with molecular dynamics simulations”, M.C.Rezende *, F.Nilo-González and N. Carrasco, J.Phys.Org.Chem., 2005, 18, 128-133

8. “Supramolecular structures of five 5-(arylmethylene)-1,3-dimethylpyrimidine-2,4,6-(1H, 3H,5H)-triones: isolated molecules, hydrogen-bonded chains and chains of fused hydrogen-bonded rings” , M.C.Rezende *, M.Domínguez, J.L.Wardell *, J.M.S.Skakle, J.N.Low and C.Glidewell, Acta Cryst. Section C, 2005, 61, 0306-0311

9. “Heteroarylisopropylamines as MAO inhibitors” , G. Vallejos, A. Fierro, M.C.Rezende *, S.Sepúlveda-Boza and M.Reyes-Parada, Bioorg.Med.Chem., 2005, 13/14, 4450-4457

10. “Evaluating the Internal Charge-transfer in Benzylidene Derivatives of N,N-Dimethylbarbituric Acid”,  M. C. Rezende *,  F. Jara  and  M. Domínguez, J.Chem.Educ. 2006, 83, 937-939.

11. “A new antibacterial clerodane diterpenoid from the resinous exudate of Haplopappus uncinatus” , A. Urzúa *, F. Jara, E. Tojo, M. Wilkens, L. Mendoza and M.C.Rezende, J. Ethnopharmacol. 2006, 103, 297-301 

12. “ A Spectral and Molecular Dynamics Simulation Study of b-Cyclodextrin Inclusion Complexes with Solvatochromic Dyes Derived from Barbituric Acid”, F. Jara, C. Mascayano, M.C.Rezende *, C.Tirapegui and A. Urzua, J.Incl.Phenom.Macroc.Chem., 2006, 54, 95-99.

13. “The interaction of solvatochromic pyridiniophenolates with cyclodextrin “, F. Jara, M. Domínguez and M.C.Rezende *, Tetrahedron, 2006, 62, 7817-7823

14. “Host-guest interactions in cyclodextrin inclusion complexes with solvatochromic dyes”,  C. Tirapegui, F. Jara, J. Guerrero and M.C.Rezende *, J.Phys.Org.Chem. , 2006, 19, 786-792

15. “3-Benzyl-2,4,6-triphenylpyrylium tetrafluoroborate”,  F.Jara, M.Domínguez, M.C.Rezende *, E.R.T.Tiekink, J.L.Wardell and S.M.S.V. Wardell *, Acta Cryst. 2006, E62, 01-03

16. “ Synthesis of 2-Aryl-1,3-propanediamines using a one-pot Knoevenagel-Michael sequence”, P. Iturriaga-Vásquez *, S. Lühr-Sierra, M.C.Rezende and B.Cassels,  J.Chil.Chem.Soc. 2006, 51,  781-783.

17. “Preparation, spectroscopic and acidity properties of two hydrazones: an organic lab experiment”, M. C. Rezende *, C. Pizarro and D. Millán, Química Nova, 2007, 30, 229-231

18. “Secondary metabolites in the flower heads of Haplopappus berterii (Asteraceae) and its relation with insect-attracting mechanisms”, A. Urzúa *, R. Santander, J. Echeverría and M. C. Rezende, J.Chil.Chem.Soc. 2007, 52, 1142-1144,

19. “Solvatochromic Hydrazone Anions Derived from Chalcones”,  D. Millán, M. Dominguez and M. C. Rezende *, Dyes and Pigments, 2008,  77, 441-445  

20. “ Electrooxidation of chlorophenols at a glassy carbon electrode in a pH 11 buffer”, C. Berríos, R. Arce, M.C.Rezende, M.S.Ureta-Zañartu *, C. Gutiérrez, Electrochimica Acta 2008, 53, 2768-2775.

21. “A Structure-Activity Study of Antibacterial Diterpenoids” A. Urzúa* , M. C. Rezende, C. Mascayano and L. Vásquez, Molecules 2008, 13, 882-891

22. “Synthesis and photoinitiation activity of macroinitiators comprising benzophenone derivatives” A.M.Rufs, A.Valdebenito, M.C.Rezende, S.Bertolotti, C.Previtali, M.V.Encinas *, Polymer, 2008, 49, 3671-3676.

23. “Antibacterial properties of 3 H-spiro[1-benzofuran-2,1-cyclohexane] derivatives from Heliotropium filifolium”, A. Urzúa *, J. Echeverria, M. C. Rezende and M. Wilkens, Molecules, 2008, 13, 2385-2393.

24. “How meaningful is the assessment of antioxidant activities in microheterogeneous media?” C. Aliaga *, M. C. Rezende and A. Arenas, Food Chem., 2009, 113, 1083-1087.

25.” Solvato- and Halo-chromism of N-(4-Oxyphenyl)-5-Nitro-2-thiophenecarboxaldimine”, M. C. Rezende *, R. Oñate, M. Domínguez and D. Millán, Spec. Letters, 2009, 42, 81-86.

26.  “Solute-solvent interactions in solutions of solvatochromic phenoxides: a dynamics simulation study”, C. Mascayano , M. C. Rezende *, C. Mendez, G. Núñez and V. Chiang, J. Sol.Chem., 2009, 38,  363-371.

27. “Solvent and temperature effects on the conformational equilibria of a dihydrobenzo[h]quinolinium fluoroborate”,  M. C. Rezende* and J. Guerrero, Magn. Res. Chem., 2009, 47, 505-510.

28. “Lipophilic contributions to the solvatochromism of analogous betaines”,  M.C.Rezende *,  R. Oñate, G. Núñez, M. Domínguez and C. Mascayano, Dyes and Pigments, 2009, 83, 391-395.

29. “A new dual probe for hydrogen abstraction”, C.Aliaga *, M.C.Rezende and C. Tirapegui, Tetrahedron, 2009, 65, 6025-6028.

30. “A fast, robust electrochemical method for the automated determination of hydrogen peroxide”, I.L.de Mattos *, M.C.Rezende, M.Areias, M.Navarro, J.Chil.Chem.Soc. 2009, 54, 414-416.

31. “Binding of arachidonic acid and two flavonoid inhibitors to human 12- and 15-lipoxygenases: a steered molecular dynamics study”, C. Mascayano*, G. Núñez, W. Acevedo and M. C. Rezende, J. Mol.Modelling,  2010, 16, 1039.

32. “Towards a unified view of the solvatochromism of phenolate betaine dyes”, M.C.Rezende * and M.Domínguez, J.Phys.Org.Chem., 2010, 23, 156-170.

33. “The cationic halochromism of phenolate betaines: a molecular dynamics and quantum mechanics study”, M. Dominguez and M.C. Rezende *, J.Iran.Chem.Soc. 2010, 7, 995-1003.

34. “The thermochromism of the ET(30) betaine in a micro-heterogeneous medium: a spectral and dynamics simulation study”, C. Aliaga, L. Briones, M.C.Rezende*, C. Tirapegui, J.Colloid Interface Sci.,  2010, 349, 565-570.

35. “Electrospray ionization mass spectrometric fragmentation of  hydroquinone derivatives”, I. Almodovar *, O. Ramírez-Rodríguez, A. Barriga, M. C. Rezende, R. Araya-Maturana, Rapid Commun. Mass Spectrom., 2011, 25, 370-378.

36. “ Sensing different micellar microenvironments with solvatochromic dyes of variable lipophilicity”, M.C.Rezende *, C. Mascayano, L. Briones and C. Aliaga, Dyes and Pigments 2011, 90, 219-224.

37. “Enhanced catalytic activity of Fe phthalocyanines linked to Au(111) via conjugated self-assembled monolayers of aromatic thiols for O2 reduction ” , I. Ponce, J. F. Silva, R. Oñate, M.C. Rezende, M. Paez, J. Pavez *, J. H. Zagal , Electrochem. Commun., 2011, 13, 1182-1185.

38. “Substituent electrophilic constants”, M.C.Rezende * and D. Millán, J.Brazil.Chem.Soc. 2011, 22, 2078-2086.

39. “Solvatochromism and Electrophilicity”, M.C.Rezende *, M.Domínguez, D. Millán and A. Aracena, Chem. Phys.Letters 2011, 514, 267-273.

40. “Substituent electrophilicities in the NMR spectra of barbituric derivatives”, M.C.Rezende *, I.Almodóvar, Magn.Res.Chem., 2012, 50, 266-270.

41. “ The positive halochromism of phenolate dyes in hydroxylic solutions of tetraalkylammonium cations” , M.C.Rezende *, M. Domínguez, A. Aracena, Spectrochim.Acta A, 2012, 87, 61-66.

42. “Electrophilicity and Solvatochromic Reversal of Pyridinium Phenolate Betaine Dyes”, M. C. Rezende *, A. Aracena, Chem. Phys.Letters, 2012, 542, 147-152.

43.“Enhancement of the Catalytic Activity of Fe Phthalocyanine for the Reduction of O2 Anchored to Au(111) via Conjugated Self-Assembled Monolayers of Aromatic Thiols As Compared to Cu Phthalocyanine”,  I. Ponce, J. F. Silva, R. Oñate, M. C. Rezende, M. A. Paez, J. H. Zagal, J. Pavez * , F. Mendizabal , S. Miranda-Rojas , A. Muñoz-Castro, R. Arratia-Pérez J. Phys. Chem. C, 2012, 116 , 15329–15341

44. “In search of the thermo/halochromism of the ET(30) pyridinium-N-phenolate betaine dye” , M. C. Rezende *, A. Aracena, Spectrochim. Acta A, 2012, 98, 18-22.

45. “A general framework for the solvatochromism of pyridinium phenolate betaine dyes”, M. C. Rezende, A. Aracena, Chem.Phys.Letters, publicado on line  (DOI: http:// dx.doi.org/ 10.1016/j.cplett. 2012.09.067)

46. “Theoretical Study of the solvatochromism of a donor-acceptor bithiophene”, Moisés Domínguez, Marcos Caroli Rezende, Sebastián Márquez, J.Mol.Modeling, 2012, publicado on line. (DOI 10.1007/s00894-012-1593-y)

47. “Remote regio- and stereocontrol by the sulfinyl group. Diels-Alder reaction of sulfinyl dienols and 8,8-dimethylnaphthalene-1,4,5(8H)-trione.”  I. Almodovar*  , W. Cardona, T. Delgado-Castro, G. Zapata-Torres, M. C. Rezende, R. Araya-Maturana, M. Carmen-Maestro, J. L. García-Ruano, Tetrahedron Assymmetry, aceptado.

Proyectos: 

Investigador responsable

  1. Fondecyt 1040001, 2004-2006, “Comportamiento anisotrópico de compuestos solvatocrómicos en microambientes heterogéneos”
  1. Fondecyt 1070124, 2007-2009 “ Interacciones soluto-solvente de sondas solvatocrómicas en solución”
  2. Fondecyt 1100022, 2010-2013,  “Novel solvato- and halo-chromic betaines: synthesis, evaluation and development of theoretical models.
  3. Fondef D10i1100,  2011-2013 “Sensores inteligentes para el control de calidad en la industria del vino”

 

Co-Investigador

  1. Fondecyt 1080234, 2008-2010, “Use of prefluorescent and radical probes for the study of medium effects on hydrogen transfer reactions.” Investigador alterno.
  1. Fondecyt 1110736, 2011-2014, “ Design and properties of new prefluorescent probes in homo – and micro-heterogeneous media”, Investigador alterno.
Otras actividades relevantes: 

Número de tesis dirigidas en los últimos 10 años:

Magister:           Dirigidas:   -                En desarrollo:   01

Doctorado:        Dirigidas:  06                En desarrollo:   03