Levicán Jaque Gloria

Levicán Jaque Gloria
Email
gloria.levican@usach.cl
Teléfono
27181125
Grados académicos /educación
Doctor (Ph.D) en Cs. Biológicas mención Microbiología. Universidad de Chile, 2003
Licenciada en Cs. Biológicas
Cargo o Título
Vicedecana de Investigación y Postgrado
Jerarquía
Asociado
Biografía /resumen / Abstrac

Our research is focused on the elucidation of the molecular elements involved in adaptation of microorganisms to environmental changes. We are especially interested in characterization of the oxidative stress response of acidophilic bioleaching bacteria used in the recovery of metals from sulfide ores.  These microorganisms are a suitable model to study this response because of they are exposed to very highly oxidative conditions such as very acid pH and extremely high metal concentration.

Our research is focused on the elucidation of the molecular elements involved in adaptation of microorganisms to environmental changes. We are especially interested in characterization of the oxidative stress response of acidophilic bioleaching bacteria used in the recovery of metals from sulfide ores.  These microorganisms are a suitable model to study this response because of they are exposed to very highly oxidative conditions such as very acid pH and extremely high metal concentration.

Otras actividades relevantes

Publicaciónes


Contreras M, Mascayano C, Chávez R, Ferrer A, Paillavil B, Levicán G. (2015). Dyp-Type Peroxidase (DypA) from the Bioleaching Acidophilic Bacterium Leptospirillum ferriphilum DSM 14647. Advanced Materials Research 1130: 23-27. 

  1. Gil-Durán C, Rojas-Aedo JF, Medina E, Vaca I, García-Rico RO, Villagrán S, Levicán G, Chávez R. The pcz1 Gene, which Encodes a Zn(II)2Cys6 Protein, Is Involved in the Control of Growth, Conidiation, and Conidial Germination in the Filamentous Fungus Penicillium roqueforti. PLoS One. (2015) Mar 26;10(3):e0120740. doi: 10.1371/journal.pone.0120740. eCollection 2015.
  2. Farah C, Levicán G, Ibba M, Orellana O. Effect of hydrogen peroxide on the biosynthesis of heme and proteins: potential implications for the partitioning of GlutRNA(Glu) between these pathways. Int J Mol Sci. (2014) Dec 11;15(12):23011-23. doi: 10.3390/ijms151223011.
  3. Valdés N, Rivera-Araya J, Bijman J, Escudero L, Demergasso C, Fernández S, Ferrer A, Chávez R, Levicán G. Draft Genome Sequence of Nitrincola sp. Strain AD6, an Arsenic-Resistant Gammaproteobacterium Isolated from a Salt Flat. Genome Announc. (2014) Nov 20;2(6). pii: e01144-14. doi:10.1128/genomeA.01144-14.
  4. Del-Cid A, Ubilla P, Ravanal MC, Medina E, Vaca I, Levicán G, Eyzaguirre J, Chávez R. Cold-active xylanase produced by fungi associated with Antarctic marine sponges. Appl Biochem Biotechnol. (2014) Jan;172(1):524-32. doi: 10.1007/s12010-013-0551-1.
  5. Eherenfeld N, Levicán G, Parada P. (2013). Heterodisulfide reductase from Acidithiobacilli is a key component involved in metabolism of reduced inorganic sulfur compounds. Adv. Mat. Res., 825: 194-197.
  6. Bustamante P, Covarrubias O, Levicán G, Katz A, Tapia P, Holmes D, Quatrini R, Orellana O. (2012). ICEAfe1, an actively excising genetic element from the biomining bacterium Acidithiobacillus ferrooxidans. Journal of Molecular Microbiology and Biotechnology (Enviada).
  7. Cárdenas JP, Moya F, Covarrubias P, Shmaryahu A, Demergasso C, Levicán G, Holmes DS, Quatrini R. (2012). Comparative genomics of the oxidative stress response in bioleaching microorganisms. Hydrometallurgy 127–128: 162–167
  8. Norambuena J, Flores R, Cárdenas JP, Quatrini R, Chávez, R, Levicán G. (2012) Thiol/Disulfide system plays a crucial role in redox protection in the acidophilic iron-oxidizing bacterium Leptospirillum ferriphilum. Plos One 7(9):e44576.
  9. Levicán G, Gómez, MJ, Chávez, R, Orellana, O, Moreno-Paz, M, Parro, V. J. (2012). Comparative genomic analysis reveals novel facts in the cytochromes of Leptospirillum spp. Levicán, G. J Mol Microbiol Biotechnol., 22: 94-104.
  10. Vaca I, Faúndez C, Maza F, Paillavil B, Hernández V, Acosta F, Levicán G, Martínez C, Chávez R. (2012). Cultivable psychrotolerant yeasts associated with Antarctic marine sponges. World J Microbiol Biotechnol (Publicada)
  11. Ravanal, M.C., Espinosa, Y., Rosa, L., Vaca, I., Polanco, R., Eyzaguirre, J., Levicán, G, Chavez, R. (2012). Glucose-induced production of a Penicillium purpurogenum xylanase by Aspergillus nidulans. Mycoscience, 53: 152-155.
  12. De Armas M, Levicán G, Katz A, Moser J, Jahn D, Orellana O. (2011). Cellular levels of heme affect the activity of dimeric glutamyl-tRNA reductase. Biochem. Biophys. Res. Com., 405: 134-139.
  13. Espinosa Y., Trebotich J., Sepúlveda F., Cadena J., Vargas-Straube M.J., Vaca I., Bull P., Levicán G., Chávez R. (2011). Production of a heterologus recombinant protein using fragments of the glyceraldehyde-3-phosphate dehydrogenase promoter from Penicillium camemberti. World J. Microbiol. Biotechnol. 27: 3019-3023.
  14. Badilla Fazzini RA, Levicán G, Parada P. (2011). Acidithiobacillus thiooxidans secretome containing a newly described lipoprotein Licanantase enhances chalcopyrite bioleaching rate. App. Microbiol. Biotechnol., 89: 771-780.
  15. De Armas-Ricard M, Levicán G, Katz A, Moser J, Jahn D, Orellana O. (2011). Cellular levels of heme affect the activity of dimeric glutamyl-tRNA reductase. Biochem. Biophys. Res. Com., 405: 134- 139.


Proyectos


Fondecyt Iniciación 1085045 3 años 2009-2011 IR

  • Fondecyt Regular 1110203 4 años 2010-2014 CI
  • Fondecyt Regular 1120746 4 años 2012-1015 IR
  • Fondecyt Regular 1150834 4 años 2015-2018 CI