Académico Depto Química Materiales

Email: 
jorge.pavez@usach.cl
Teléfono: 
227 181 030

Abstract

The research interest involves the development and characterization of surfaces with nanostrcutures based on self assembled array. These surfaces are focalized for electrochemical applications of interest within the field of the sensors and electrocatalysis.

Línea(s) de investigación: 
Físico-Química de Superficies Nanoestructuradas. Aplicaciones Electroquímicas.
Jerarquía: 
Titular
Grados académicos /educación: 
Doctorado en Química, Universidad de Santiago de Chile. 2001
Publicaciones: 

(Periodo 2016-2020)

21.- “Synthesis of mono/dinuclear rhenium(i) tricarbonyl substituted with 4-mercaptopyridine related ligands: spectral and theoretical evidence of thiolate/thione interconversion”, Gomez, A; Jara, G.; Flores, E; Maldonado, T.; Godoy,F.; Munoz-Osses,; Vega, A.; Mera, R.; Silva, C.P.; Pavez, J., NEW JOURNAL OF CHEMISTRY, 44, 33 (2020)14171-14179

20.- “Chitosan-Based Nanoparticles for Intracellular Delivery of ISAV Fusion Protein cDNA into Melanoma Cells: A Path to Develop Oncolytic Anticancer Therapies”, Robles-Planells, C.; Guerrero, G. Sanchez; Barrera-Avalos, C.; Matiacevich, Silvia;  Rojo, L. E.; Pavez, J. Salas-Huenuleo, E. Kogan, M.;  Escobar, A.;  Milla, L.A.; Fernandez, R.; Imarai, M.; Spencer, E.; Huidobro-Toro, J.uan P.; Acuna-Castillo, C., MEDIATORS OF INFLAMMATION   Volumen: ‏ 2020 (2020) Nº 8680692

19.- “Chitosan-Based Delivery of Avian Reovirus Fusogenic Protein p10 Gene: In Vitro and In Vivo Studies towards a New Vaccine against Melanoma” ,Robles-Planells, C; Barrera-Avalos, C; Rojo, LE; Spencer; Cortez-San Martin, M; Matiacevich, S; Pavez, J; Milla, LA; Navarro, FD (Navarro, Franco D.)[ 1,2 ] ; Martinez, BA., BIOMED RESEARCH INTERNATIONAL   Volumen: ‏ 2020, Nº4045760 (2020).

18.- “Applying the voltammetry of microparticles to assess the metal ion excess following a precipitation reaction. The determination of arsenic”,J. Espinoza, J. Pavez, E. Gonzalez, C.Ramirez, M. Páez, M. Gulppi, JOURNAL OF SOLID STATE ELECTROCHEMISTRY, 23 (2019) 3225-3229.

17.-“Surfaces based on amino acid functionalized polyelectrolyte films towards active surfaces for enzyme immobilization”, X. Briones, V.Villalobos, Y.Queneau, C. Silva D., R. Muñoz, H.E. Ríos, J. Pavez, M. Páez, R. Cabrera, L. Tamayo, M. D. Urzúa, MATERIALS SCIENCE AND ENGINEERING: C, 104, (2019) Article 109938

16.- “Evidence of the redox role of ferrocenyl-imine derivatives in the presence of copper (II) ions”, N. Agurto, C. P. Silva, G. S. Jara, T. Maldonado, E. Flores, C. F. Morales, A. Oliver, F. Godoy, J. Pavez, ELECTROCHIMICA ACTA, 318 (2019)479-485

15.- “Amino Acid-Functionalized Polyelectrolyte Films as Bioactive Surfaces for Cell Adhesion”, M. S. Leal, X. Briones, V. Villalobos, Y. Queneau, A. Leiva, H. E. Ríos, J. Pavez, C. P. Silva, C. Carrasco, Andrónico Neira-Carrillo, A. D. Roth, L. Tamayo, M. D. Urzúa, ACS APPL. MATER. INTERFACES, 11 (22) (2019) pp 19751-19762.

14.- Inhibiting pathogen surface adherence by multilayer polyelectrolyte films functionalized with glucofuranose derivatives, V. Villalobos, A. Leiva, H.E. Ríos, J.Pavez, C. P. Silva, M.ohammed Ahmar, Y. Queneau, J.M. Blamey, Fr. P. Chávez, M. D. Urzúa, ACS APPL. MATER. INTERFACES, 10 (33) (2018) pp 28147–28158.

13.- Characterization of poly-D-mannuronate and poly-L-guluronate block fractions from sodium alginate and preparation of hydrogels with poly (vinylalcohol) F. Martínez-Gómez , J. Guerrero, Betty Matsuhiro, J. Pavez, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 111 (2018) 935–946.

12.- Large scale cathodic exfoliation of graphite using deep eutectic solvent and water mixture, D. Vásquez-Sandoval , J. Pavez, C. Carlesi, A. Aracena, FULLERENES, NANOTUBES AND CARBON NANOSTRUCTURES (2018), 26,123–129.

11.- “Tailoring electroactive surfaces by non-template molecular assembly. Towards L-cysteine electrooxidation”, M. Santander-Nelli, C. P. Silva, J. Espinoza-Vergara, J.F. Silva, C. Olguín, D. Cortés-Arriagada, J.H. Zagal, F. Mendizabal, I.Díez-Pérez, J. Pavez, ELECTROCHIMICA ACTA, 254 (2017) 201–213

10.-“Gold nanostructures on self-assembled monolayers activity for epinephrine, noradrenaline and dopamine”, S. Ramirez, N. Silva, M.P. Oyarzun, J. Pavez, J. F. Silva JOURNAL OF ELECTROANALYTICAL CHEMISTRY799 (2017) 349-357.

9.-In vitro release of metformin hydrochloride from sodium alginate/polyvinyl alcohol hydrogels, F. Martínez-Gómez, J. Guerrero, B.Matsuhiro, J.Pavez, CARBOHYDRATE POLYMERS, 155 (2017) 182-191.

8.-Synthesis and characterization of organometallic chalcones functionalized with a crown ether fragment. Spectroscopic and electrochemical behavior, Nicolás Agurto, Tamara Maldonado, Fernando Godoy, Alejandra Gómez, Carlos P. Silva, Jorge Pavez, Guillermo Ferraudi, Allen Oliver, A. Graham Lappin, JOURNAL OF ORGANOMETALLIC CHEMISTRY, 827, (2017), 32-40.

7.- Etcheverry-Berríos, Á.; Olavarría, I.; L. Perrin, M.; Díaz-Torres, R.; Jullian, D.; I. Ponce; J. H. Zagal; J.Pavez; S. O., Vásquez; S. J. van der Zant,  H.; Dulić, D.; Aliaga-Alcalde, N.; Soler, M. “Multiscale Approach to the Study of the Electronic Properties of Two Thiophene Curcuminoid Molecules”, CHEMISTRY - A EUROPEAN JOURNAL, 22 (2016) 12808-12818. DOI: 10.1002/chem.201601187

6.-C. P. Silva, M. Santander-Nelli, C. Vera-Oyarce, J.F. Silva, A. Gómez, L. Muñoz, J. H. Zagal, M.Gulppi,  J. Pavez, “Poly-aniline Nanostructures Electrode. Morphological Control by Hybrid Template, JOURNAL OF SOLID STATE ELECTROCHEMISTRY, 20 (2016) 11-75-1180.

5.-Franco Arias, Andrés Mansilla, Betty Matsuhiro, Jorge Pavez, Rodrigo Torres, Mauricio Yáñez-S, Carrageenans from nuclear phases of subantartic Mazzaella laminarioides (Gigartinales, Rhodophyta) and graft copolymerization of alkali modified carrageenan with acrylamide, JOURNAL OF APPLIED PHYCOLOGY, 28 (2016) 1275-1286.

4.-Ponce, I., Aragonès, A.C., Darwish, N., Pla-Vilanova, P., Oñate, R., Rezende, M.C., Zagal, J.H., Sanz, F., Pavez, J., Díez-Pérez, I., (2015) Building Nanoscale Molecular Wires Exploiting Electrocatalytic Interactions, ELECTROCHIMICA ACTA, 179 (2015) 611.

3.-Gulppi, M., Pavez, J., Zagal, J.H., Sancy, M., Azocar, M., Sholtz, F., Páez, M.A. Stripping voltammetry microprobe (SPV): Substantial improvements of the protocol (2015) JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 745, pp. 61-65.

2.-Godoy, F., Gómez, A., Agurto, N., Muñoz, M., Segura, R., Silva, C.P., Pavez, J., Zagal, J.H., Klahn, A.H., Fuentealba, M., Ibañez, A., Garland, M.T.,Synthesis, reactivity, electrochemical behaviour, and molecular structure of crown ether cyrhetrene complexes, (2015) JOURNAL OF ORGANOMETALLIC CHEMISTRY, 788, pp. 42-48.

1.-Martínez-Gómez, F., Encinas, M.V., Matsuhiro, B., Pavez, J. 11Preparation and swelling properties of homopolymeric alginic acid fractions/poly(N-isopropyl acrylamide) graft copolymers, (2015) JOURNAL OF APPLIED POLYMER SCIENCE, 132 (32),  42398.

Proyectos: 
Investigador Responsable
1. FONDECYT REGULAR,  Nº1171449, “Molecular Electronics; a platform to study the electrocatalysis of Oxygen Reduction Reaction”. 2017-2020
2. FONDECYT REGULAR,  Nº1131062, “Molecularly Assembled Electrodes”. 2013-2016.
3. FONDECYT REGULAR, Nº 1090627, “Fabrication of Large Array of Oriented Polyaniline Nanowires by Hybrid Template”. 2009-2012.
4. FONDEQUIP, Nº EQM-160036 “Adquisición de Microscopio de Efecto Tunel y Fuerza Atómica para estudios de transporte electrónico en interfaces y moléculas individuales”. 2017-2019
5. CONYCYT (ANID) INSERCIÓN CAPITAL HUMANO AVANZADO EN LA ACADEMIA; PAI-CONICYT,  Nº 79170101, “Química Organometálica Interfasial; Hacia catalizadores Heterogéneos de sitios únicos”. 2017-2019.
6. CONYCYT (ANID) INSERCIÓN CAPITAL HUMANO AVANZADO EN LA ACADEMIA; PAI-CONICYT, “Electrónica Molecular; procesos de Transporte de Carga Interfasial” Nº 79150041. 2015-2017.
7. FONDECYT POSTDOCTORADO, Nº3010009, “Estudio de la Morfología y Cinética de Crecimiento de Biocerámicas”.  2001-2004.
 
Investigador Asociado
1. FONDECYT Nº 11801037, “Reactivity Descrptors for MNx Non-Precious Metal Complexes as Molecular Catlalysis fro Electrochemical reaction”", 2018-2021.
2. FONDECYT Nº 1160167, “Quantitative Solutions Analysis by Voltammetry of Microparticles”, 2016-2020.
3. FONDECYT 1100603, "Surface growth of CaCO3 in the presence of dermatan sulfated molecules: study of morphology and mechanical properties of {104} facet by Atomic Force Microscopy", 2010-2012.
4. INICIATIVA CIENTÍFICA MILENIO, RC120001, “Molecular Engineering for Catalysis, Electrocatalysis and Nanosensors”. 2016-2016.
5. INICIATIVA CIENTÍFICA MILENIO, P07-006-F, “Molecular engineering and supramolecular chemistry for catalysis, electrocatalysis, remediation and energy conversion”. 2010-2012.
6. DICYT-USACH: “Determinación estructural y modificación química de polisacáridos de algas”, 2011-2012.
7. Programa Bicentenario en Ciencia y Tecnología-Conicyt, “Espectrometrías y Microscopías;”. 2006 -2008.
8. CONICYT, FONDECYT LÍNEAS COMPLEMENTARIAS., “Procesos de transferencia de carga en electrocatalisis y corrosion electroquimica”. 2005-2006.
 
Postdoctoral Training.
• Dra. Elizabeth Imbarak Candia. POSTDOC FONDECYT 2020-2022
• Dr. Nicolás Agurto Doren. POSTDOC FONDECYT 2020-2022
• Dra. Alejandra Gómez San Martín. POSTDOC FONDECYT 2016-2018
• Dra. Ingrid Ponce Hormazábal; POSTDOC FONDECYT 2013-2015.
Otras actividades relevantes: 

Número de tesis dirigidas en los últimos 10 años:



Doctorado:           Dirigidas:  6                   En desarrollo: 4

Magíster:              Dirigidas:  3                   En desarrollo: 0

 

Referee de revistas internacionales

  • Materials Chemistry and Physics.
  • Inorganic Chemistry.
  • Bioelectrochemistry.
  • Materials Letters.
  • Journal of Chilean Chemical society.

                       

Revisor de proyectos

  • FONDECYT; Postdoctorado, Iniciación, Regular.
  • CORFO.

 

Participación en claustro de doctorados
 
  • Doctorado en  Química, Facultad de Química y Biología, USACH.
  • Doctorado en Ciencias de La Ingeniería, Mención Ciencia de los Materiales, USACH
Email: 
ruth.yanez@usach.cl
Jerarquía: 
Instructor
Email: 
jorge.vidal.f@usach.cl
Jerarquía: 
Asistente
Email: 
karen.manquian@usach.cl
Jerarquía: 
Asistente
Email: 
miguel.gulppi.c@usach.cl
Jerarquía: 
Asistente
Email: 
alejandra.gomezs@usach.cl
Jerarquía: 
Asistente
Email: 
jaime.pizarror@usach.cl

Abstract:

Our research focuses on the development of analytical methodologies using electrochemical sensors based on disposable and low-cost screen-printed electrodes modified from the synthesis of carbon nanostructures, evaluating their electrochemical response for the determination of psychoactive substances by voltammetric techniques.

Jerarquía: 
Asistente
Grados académicos /educación: 
Doctor en Química, Universidad de Santiago de Chile, 2014.
Publicaciones: 

1) Development of electrochemical sensors for the determination of selenium using gold nanoparticles modified electrodes (2015) Sensors and Actuator B: Chemical         Rodrigo Segura*, Jaime Pizarro, Karina Díaz, Alan Placencio, Fernando Godoy, Eduardo Pino and Francisco Recio

2) New aryloxy-quinone derivatives as potential anti-Chagasic agents: synthesis, trypanosomicidal activity, electrochemical properties, pharmacophore elucidation and 3D-QSAR analysis (2015) RSC Advances

Karina Vázquez, Christian Espinosa-Bustos, Jorge Soto-Delgado, Ricardo A. Tapia, Javier Varela, Estefanía Birriel, Rodrigo Segura, Jaime Pizarro, Hugo Cerecetto, Mercedes González, Margot Paulino* and Cristian O. Salas*

3) Determination of lead and cadmium in water samples by adsorptive stripping voltammetry using a bismuth film/1-Nitroso-2-Napthol/Nafion modified glassy carbon electrode (2016) Journal of International Electrochemical Science

Rodrigo A. Segura*, Alejandra D. Castillo, Jaime A. Pizarro, María P. Oyarzun, Karina J. Díaz, Alan B. Placencio

4) An electrochemical sensor for the determination of Cu(II) using a modified electrode with ferrocenyl crown ether compound by square wave anodic stripping voltammetry. (2017) Sensors and Actuator B: Chemical

Erick Flores, Jaime Pizarro, Fernando Godoy, Rodrigo Segura*, Alejandra Gómez, Nicolás Agurto and Pamela Sepúlveda

5) Anodic stripping voltammetric determination of lead using a chemically modified electrode based on aza crown ether (2017) Journal of the Chilean Chemical Society

Rodrigo Segura*, Karina Díaz, Jaime Pizarro, Alan Placencio, Diego Tapia and Angelo Fajardo

6) Synthesis and characterization of the first cyrhetrenyl-appended calix[4]arene macrocycle and its application as an electrochemical sensor for the determination of Cu(II) in bivalve mollusks using square wave anodic stripping voltammetry (2018) Sensors and Actuator B: Chemical

Jaime Pizarro, Erick Flores, Victor Jimenez, Tamara Maldonado, Claudio Saitz, Andres Vega, Fernando Godoy and Rodrigo Segura

7) Determination of norepinephrine using a glassy carbon electrode modified with graphene quantum dots and gold nanoparticles by square wave stripping voltammetry (2018) Journal of Applied Electrochemistry

Autor(es) A. Fajardo, D. Tapia, J. Pizarro*, R. Segura* and P. Jara

8) Electroanalytical determination of Cd(II) and Pb(II) in bivalve mollusks using electrochemically reduced graphene oxide-based electrode (2019) Electroanalysis

Jaime Pizarro*, Rodrigo Segura*, Diego Tapia, Soledad Bollo and Paulina Sierra Rosales

9) New aryloxy-quinone derivatives with promising activity on Trypanosoma cruzi (2020) Archiv der Pharmazie

Christian Espinosa-Bustos, Karina Vázquez, Javier Varela, Hugo Cerecetto, Margot Paulino, Rodrigo Segura, Jaime Pizarro, Brenda Vera, Mercedes González, Ana M. Zarate, Cristian O. Salas*

10) Ulva compressa from Copper-Polluted Sites Exhibits Intracellular Copper Accumulation, Increased Expression of Metallothioneins and Copper Containing Nanoparticles in Chloroplasts (2021) International Journal of Molecular Sciences

Daniela Espinoza, Alberto González, Jaime Pizarro, Rodrigo Segura, Daniel Laporte, Fernanda Rodríguez-Rojas, Claudio A. Sáez and Alejandra Moenne*

11) Inexpensive and green electrochemical sensor for the determination of Cd(II) and Pb(II) by square wave anodic stripping voltammetry in bivalve mollusks  Food Chemistry (2020)

Jaime Pizarro*, Rodrigo Segura*, DiegoTapia, Freddy Navarro, Francesca Fuenzalida and María Jesús Aguirre

12) A simple graphene modified electrode for the determination of antimony(III) in edible plants and beverage (2022) Food Chemistry

Fabiana Liendo, Amaya Paz de la Vega, Maria Jesus Aguirre, Fernando Godoy, Angel A.Martí, Erick Flores* , Jaime Pizarro* and Rodrigo Segura*

13) Fast and simple preparation of a sensor based on electrochemically reduced graphene oxide (rGO) for the determination of zopiclone in pharmaceutical dosage by square wave adsorptive stripping voltammetry (SWAdsV) (2022) Electroanalysis

Freddy Navarro, Rodrigo Segura, Fernando Godoy, Angel Martí, Carolina Mascayano, Maria Jesus Aguirre*, Erick Flores* and Jaime Pizarro*

Proyectos: 

1) Proyecto Postdoctorado Nacional N° 3200165: “En la búsqueda de un sensor para la determinación in situ de drogas Z en fluidos orales”. Investigador Responsable

2) Proyecto Subvención a la Instalación en la Academia N°85220089: ‘‘Creación de área interdisciplinaria de detección de drogas mediante el desarrollo de sensores in situ para drogas de abuso en la Facultad de Química y Biología de la Universidad de Santiago de Chile’’ (2022-2025). Investigador Responsable

3) Proyecto FONDECYT Iniciación N° 11230219 “On-site sensor for the determination of chemical submission drugs” (2023-2026). Investigador Responsable

Congresos: 
1) 10th International Conference On Instrumental Methods Of Analysis: Modern Trends And Applications Heraklion, Greece. September 2017.
An electrochemical sensor based on electrochemically reduced graphene for the simultaneous determination of Pb(II) and Cd(II) by square wave anodic stripping voltammetry (swasv)
J. Pizarro and R. segura.
2) Pittcon Conference Orlando, Florida, USA. February 2018.
J. Pizarro, R. Segura, S. Bollo, P. Sierra. Analytical validation for determination of Cd(II) and Pb(II) in bivalve mollusks through square wave anodic stripping voltammetry using a modified electrode with electrochemically reduced graphene
 
Email: 
rudy.martin@usach.cl
I am devoted to Supramolecular Chemistry and Nanotechnology. My research is focused on combining both topics to design and prepare new materials inspired by Nature. I prepare cyclodextrin polymers, either crosslinked or lineal, to caps noble metal or semiconductor nanoparticles creating a synergistic effect between the receptor/recognizing capabilities of cyclodextrin and the intrinsic properties of nanoparticles. Nanoparticles are also chemically or physically modified on its surface to
achieve new physical properties (hydrophobic/hydrophilic compromise, shape, luminescent, among others).  
My latest project (Fondecyt-11190555) aims to prepare supramolecular copolymer-binders based on adamantane and cyclodextrin host-guest interaction to assemble silicon anodes for Li-Ion batteries. Silicon anodes show a much higher  gravimetric capacity than the actual carbon anodes but suffer from capacity fading due to their volume expansion (X300) upon lithiation and de-lithiation process. The reversible supramolecular interactions of binders are desirable for the healing of silicon particles during the battery cycling life.
Additionally, we prepare superhydrophobic composite membranes for desalinization of seawater, using membrane distillation technology. To achieve superhydrophobic membranes we used surface-modified nanoparticles (alkyl fluorinated-capped CuO or silica nanoparticles) to change the membrane properties by decreasing the surface energy.
Línea(s) de investigación: 
Química Supramolecular y Nanotecnología
Jerarquía: 
Asistente
Grados académicos /educación: 
Postdoctorado, Pontificia Universidad Católica de Chile, 2018-2020
Postdoctorado, Universidad Andrés Bello 2014-2017
Doctor en Química, Universidad de la Habana-Universidad de Bremen, 2013
Licenciado en Química, Universidad de la Habana, 2003
Publicaciones: 
1. “Preparation of functional coating films using breath figure (BF) method and the study of morphological, optical and wettability behavior with varying experimental conditions” A. Boulett, O. Marambio, R. Martin-Trasanco, J.Sánchez, W. Alavia, D. Oyarzún, G. Pizarro; International Journal of Polymer Analysis and Characterization, 2023, DOI: https://doi.org/10.1080/1023666X.2023.2175167
 
2. “Spraying Fluorinated Silicon Oxide Nanoparticles on CuONPs@CF-PVDF Membrane: A Simple Method to Achieve Superhydrophobic Surfaces and High Flux in Direct Contact Membrane Distillation” Z. Lenac, C. Saldías, C. Terraza, A. Leiva, J. Koschikowski, D. Winter, A. Tundidor-Camba, R. Martin-Trasanco, Polymers, 2022, 14 (23), 5164, DOI: https://doi.org/10.3390/polym14235164
 
3. “Design and Study of a Photo-Switchable Polymeric System in the Presence of ZnS Nanoparticles under the Influence of UV Light Irradiation” G del C. Pizarro, W. Alavia, K. González, H. Díaz, O. G. Marambio, R. Martin-Trasanco, J. Sánchez, D. P. Oyarzún and A. Neira-Carrillo. Polymers, 2022, 14(5), 945. DOI: https://doi.org/10.3390/polym14050945
 
4. “Polycaprolactone-β-cyclodextrin polymer composite films as potential biopolymers for drug releases” Francesca Sepúlveda, Julio Sanchez Poblette, Diego P. Oyarzun, Fidel E. Rodríguez-González, Alain Tundidor-Camba, Claudio García-Herrera, Paula A. Zapata, Guadalupe del C. Pizarro and Rudy Martin-Trasanco* Journal of Inclusion Phenomena and Macromolecular Chemistry. 2022, DOI: https://doi.org/10.1007/s10847-021-01101-6
 
5. “Exploration of copper oxide nanoneedle electrosynthesis applied in the degradation of methylene blue”. D. P. Oyarzún , A. Tello, J. Sánchez, A. Boulett, O. E. Linarez-Pérez, R. Martin-Trasanco, G. del C. Pizarro, M. Flores, C. Zúñiga. Nanomaterials, 2021, https://doi.org/10.3390/nano11112994.
 
6. “Preparation of photoactive ZnS-composite porous polymer films: Fluorescent and morphological properties” Guadalupe Del C. Pizarro, Wilson Alaviaa, Rudy Martin-Trasanco, Oscar G. Marambio, Julio Sánchez and Diego P. Oyarzún. Designed Monomers and Polymers, 2021; 24, 320. DOI: https://doi.org/10.1080/15685551.2021.1989151
 
7. “A new porous organic polymer containing Tröger's base units: Evaluation of the catalytic activity in Knoevenagel condensation reaction” Fidel E. Rodríguez-González, Vladimir Niebla, M.V.Velázquez-Tundidora, Luis H.Tagle, Rudy Martin-Trasanco, Deysma Coll, Pablo A. Ortiz, Néstor Escalona, Edwin Pérez, Ignacio A. Jessoph, Claudio A. Terraza, Alain Tundidor-Camba; Reactive and Functional Polymers, 2021, 167. DOI: https://doi.org/10.1016/j.reactfunctpolym.2021.104998
 
8. “PVDF Composite Membranes with Hydrophobically-Capped CuONPs for Direct-Contact Membrane Distillation” Cesar Saldías, Claudio Terraza, Angel Leiva, Joachim Koschikowski, Daniel Winter, Alain Tundidor-Camba, Rudy Martin-Trasanco, Nanomaterials 2021, 11, 1497, DOI: https://doi.org/10.3390/nano11061497
 
9. “Electrodeposition of Cu 2 O nanostructures with improved semiconductor properties”, Andrés Boulett, Guadalupe del C. Pizarro, Rudy Martin-Trasanco, Julio Sánchez, Federico Tasca, Omar E. Linarez Pérez, Alejandra Tello, Diego P. Oyarzún. Cogent Engineering, 2021 8:1, DOI: https://doi.org/10.1080/23311916.2021.1875534
 
10. “New Poly(imide)s Bearing Alkyl Side-Chains: A Study on the Impact of Size and Shape of Lateral Groups on Thermal, Mechanical, and Gas Transport Properties” Fidel E. Rodríguez-González, Germán Pérez, Vladimir Niebla, Ignacio Jessop, Rudy Martin-Trasanco, Deysma Coll, Pablo Ortiz, Manuel Aguilar-Vega, Luis H. Tagle, Claudio A. Terraza, Alain Tundidor-Camba, Membranes, 2020, 10, DOI:  https://doi.org/10.3390/membranes10070141
 
11. “Hydrogels containing carboxyl groups for the sorption of methylene blue in aqueous solution” Estefanía Oyarce, Guadalupe Del C. Pizarro, Diego P. Oyarzún, Rudy Martin-Trasanco, Julio Sánchez. Mater. Today Commun, 2020, 25, DOI: https://doi.org/10.1016/j.mtcomm.2020.101324
 
12. “Alkoxide structure effect on size and size distribution of Ag, Au and Ag@Au nanoparticles, prepared via alkoxide mild reduction in water” Pedro D. Ortiz, Judith Castillo-Rodriguez, Alicia M. Díaz-García, Rudy Martin-Trasanco, Ximena Zarate, Mónica Benito, Elies Molins, Eduardo Schott, Mater. Sci. Eng., B. 2020, 258, DOI: https://doi.org/10.1016/j.mseb.2020.114573
 
13. “Nanosized spherical and porous films based on poly(acrylic acid)-b-poly(N-phenylmaleimide) and poly(hydroxypropyl metacrylate)-b-poly(N-phenylmaleimide” Guadalupe del C Pizarro, Oscar G Marambio, Manuel Jeria-Orell, Diego P Oyarzún, Rudy Martin-Trasanco, Julio Sánchez, Cogent Engineering, 2020, 7, DOI: https://doi.org/10.1080/23311916.2020.1744920
 
14. “Morphological, optical and wettability characterization of honeycomb patterned films based on self-assembling copolymer under thermal annealing”, Guadalupe del C. Pizarro, Oscar G. Marambio, Manuel Jeria-Orell, Julio Sánchez, Diego P. Oyarzún, Rudy Martin-Trasanco, Fernando Novio; Chem. Phys. 2020; 53, DOI: https://doi.org/10.1016/j.chemphys.2020.110715
 
15. "Microporous hybrid films from amphiphilic copolymers: Surface coated with ZnS nanoparticles by using the breath figure (BF) methodology" Guadalupe. C. Pizarro, Oscar. G. Marambio, Rudy Martin-Trasanco, Julio Sánchez, Manuel Jeria-Orell, Diego P. Oyarzún, Chem. Paper, 2020, DOI: https://doi.org/10.1007/s11696-020-01091-8
 
16. “Synthesis and characterization of new spirobisindane-based poly(imide)s. Structure effects on solubility, thermal behaviour and gas transport properties”; I.A. Jessop, D. Bravo, E. Durán, F.E. Rodríguez-González, L.H. Tagle, D. Coll, P. Ortiz, Y. Mirabal, M. Aguilar-Vega, R. Martin-Trasanco, C.A. Terraza and A. Tundidor-Camba; J. Appl. Pol. Sci; 2020, DOI: https://doi.org/10.1002/app.48944
 
17. “From Concentrated Dispersion to Solid β-Cyclodextrin Polymer-Capped Silver Nanoparticle Formulation: A Trojan Horse Against Escherichia coli”: Rudy Martin-Trasanco; Giovanna Anziani-Ostuni; Hilda Esperanza Esparza- Ponce; Pedro Ortiz; María E. Montero-Cabrera; Diego P. Oyarzún; César Zúñiga; José Manuel Pérez-Donoso; Guadalupe del C. Pizarro; Ramiro Arratia-Pérez., ChemistrySelect, 2019, 4 (34), (10092-10096). DOI: https://doi.org/10.1002/slct.201901406.
 
18. “Porous Surface Films With Tunable Morphologies and Hydrophobic Properties Based on Block Copolymer Under the Effects of Thermal Annealing.” Pizarro, Guadalupe del C., Marambio, Oscar G., Jeria-Orell, Manuel; Oyarzún, Diego P., Martin-Trasanco, Rudy., Sánchez, Julio., Frontiers in Chemistry, 2019, 7, 1. DOI: https://doi.org/10.3389/fchem.2019.00181
 
19. In-situ preparation of CdTe quantum dots capped with a -cyclodextrin-epichlorohydrin polymer. Polymer influence in nanocrystals size and optical properties. Rudy Martin-Trasanco*, Hilda E. Esparza-Ponce, Pedro D. Ortiz, Diego Oyarzun, Cesar Zuñiga, Maria E. Montero-Cabrera, Alain Tundidor-Camba, Guadalupe del C. Pizarro, Ramiro Arratia-Pérez, Nanomaterials, 2018, 8(11), 948. DOI: https://doi.org/10.3390/nano8110948
 
20. “Two New Fluorinated Phenol Derivatives Pyridine Schiff bases: Synthesis, Spectral, Theoretical Characterization, Inclusion in Epichlorohydrin-β-cyclodextrin Polymer, and Antifungal Effect” Alexander Carreño, Leonardo Rodríguez, Dayán Páez-Hernández, Rudy Martin-Trasanco, César Zúñiga, Diego P. Oyarzún, a Manuel Gacitúa, Eduardo Schott, Ramiro Arratia-Pérez, Juan A. Fuentes. Frontiers in Chemistry, 2018, 6, Article Number 312, DOI: https://doi.org/10.3389/fchem.2018.00312
 
21. “Preparation of CuONPs@PVDF/non-woven polyester composite membrane: structural influence of nanoparticles addition” Ángel Leiva, Rudy Martin-Trasanco, Cesar Saldías, Marjorie González, Claudio A. Terraza, Alain Tundidor-Camba. Polymers, 2018, 10 (8), pp.862; DOI: https://doi.org/10.3390/polym10080862
 
22. “Synthesis of Au Nanoparticles Assisted by Linker-Modified TiO 2 Nanoparticles" Ortiz, Pedro; Castillo-Rodríguez, J; Zarate, X; Martin-Trasanco, R; Benito Vélez, M; Mata, I; Molins, E; Schott, E. Langmuir, 2018, 34 (32), pp.9402, DOI: 10.1021/acs.langmuir.7b04195
 
23. “Synthesis, Characterization and Relativistic DFT Studies of fac-Re(CO) 3 (isonicotinic acid) 2 Cl complex”  C. Zúñiga; D. P. Oyarzún; R. Martin-Transaco; M. Yáñez; A. Tello; M. Fuentealba; P. Cantero-Lopéz, R. Arratia-Pérez., Chem. Phys. Lett., 2017, 688, pp. 66-73, DOI: https://doi.org/10.1016/j.cplett.2017.09.065
 
24. "Monitoring Morphological and Optical Properties on Hybrid Porous Polymer Films” .Pizarro, G. del C., Marambio, O. G., Jeria-Orell, M., Oyarzún, D. P., Martin-Trasanco, R., & Sánchez, J. (2017). International Journal of Polymer Analysis and Characterization. http://doi.org/10.1080/1023666X.2017.1370804
 
25. “Reduction of Au(III) by a β-cyclodextrin polymer in acid medium. A stated unattainable reaction” Martin-Trasanco, R., Cao, R., Esparza-Ponce, H. E., Montero-Cabrera, M. E., & Arratia-Pérez, R. Carbohydrate Polymers, 2017, 175, 530–537. http://doi.org/10.1016/j.carbpol.2017.08.013
 
26. “Synthesis and morphological characterization of nanocomposite based on anodic TiO 2 nanotubes and Poly(n-maleoyl Glycine-co-acrylic acid)”. Oyarzún, D.P; Pizarro, G.C; Asenjo, A.; Tello, A.; Martin-Trasanco, R.; Zúñiga, C.; Sánchez, J.; Arratia-Pérez, R.; J. Chil. Chem. Soc., 2017, 62, pp. 3562-3564
 
27. "Electrochemical synthesis, optical properties and morphological characterization of ZnO/Poly(N-PhMI-co-HEMA) nanocomposite". Oyarzún, D. P.; Tello, A.; Pizarro, G.C.; Martin-Trasanco, R.; Zúñigaa, C.; Perez-Donoso, J.; Arratia-Perez. R.; Journal of Electroanalytical Chemistry, 2017,799, pp.358-3622, DOI: http://doi.org/10.1016/j.jelechem.2017.06.039
 
28. “Small, stable and biocompatible gold nanoparticles capped with a -cyclodextrin polymer”. R. Martin-Trasanco, R. Cao, Hilda E. Esparza-Ponce, L. García-Pupo and Maria E. Montero-Cabrera. RSC. Adv, 2015, pp. 98440-98446. http://doi.org/10.1039/c5ra19974c
 
29. “Self-assembly of a Ru(II)-deuteroporphyrin lipoic acid derivative on Au(111) surfaces” R. Martin-Trasanco, R. Cao, F-P Montforts. , J. Porphyrins Phthalocyanines, 2015. Vol. 19, pp 10014-10020. http://doi.org/10.1142/S1088424615500704
 
30. “An unusual self-assembly of deuteroporphyrin 4-aminothiophenol derivative on Au(111) surfaces.” R. Martin, R. Cao, F-P. Montforts, Paul-Ludwig M. Noeske, New J. Chem. 2013. Vol. 67 pp. 1610-1615, DOI: http://doi.org/10.1039/c3nj00118k
 
31. “Interaction of nitric oxide with Ru(II) complexes of deuteroporphyrindimethylester derivatives”, R. Martin, F-P. Montforts, R. Cao, A M. Esteva, J. Porphyrins Phthalocyanines, 2009. Vol. 13, pp 35-40. DOI: http://doi.org/10.1142/S1088424609000188
 
32. “Solubility and Kinetic Release Studies of Naproxen and Ibuprofen in Soluble Epichlorohydrin--cyclodextrin Polymer”, R. Martin, I Sanchez, R. Cao and J. Rieumont, Supramol Chem, 2006 Vol. 18 (8), pp. 627–631. DOI: http://doi.org/10.1080/10610270601088073
 
33. “Complexation of Bis(morpholyldithiocarbamato)copper(II), a Superoxide Scavenger, in -Cyclodextrins”, R. Martin, A. Fragoso and R. Cao, Supramol. Chem, 2003 Vol. 15 (3), pp. 171–175. DOI: http://doi.org/10.1080/1061027031000078266
Premios y Honores: 
Prize of the Cuban Academy of Sciences 2014 on “Biomoléculas autoensambladas sobre superficies de oro con aplicaciones en la nanotecnología” main autor with Dr. Darío González Abradelo and Prof. Dr. Roberto Cao Vázquez.
Investigaciones : 
As part of the Fondecyt 11190555 project, we are preparing silicon anodes using linear copolymers of polyacrylic acid with β-cyclodextrin and adamantane as binding agents. We study the correlation of polymers structure/composition with the self-healing properties on silicon. Our maxima goal is to prepare stable silicon anodes with long cycling life (>500 cyles) and with gravimetric capacity close to the theoretical. The research includes:
i) Designing and preparing vinyl monomers of β-cyclodextrin and adamantane, co-polymerizing them with acrylic acid, and characterizing the resulting products.
ii) Preparing silicon anodes using the synthesized polymers as binding agents 
iii) Assembling half-cells, performing electrochemical characterization, and assessing cycling performance (gravimetric capacity, coulombic efficiency, and charge/discharge rate capability).
 
 
Proyectos: 
Fondecyt
  • 2019-2023: Grant from the Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT), Chile. Title: “Developing Binder Polymers Based On Multivalent Interactions For Silicon Anodes In Lithium-Ion Rechargeable Batteries” FONDECYT-Iniciación-11190555. (main researcher)
  • 2014-2017: Grant from the Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT), Chile. Title: “Quantum dots de CdSe y CdTe encapsulados con derivados de polímeros de ciclodextrinas: Un potencial nanosistema en el diagnóstico y tratamiento de células cancerígenas” FONDECYT-3150205. (main researcher)

CORFO:

  • 2018-2020: Grant from the Corporación de Fomento de la Producción (Corfo), “Preparation of superhydrophobic NPs@PVDF/Non-Woven Polyester composite membrane for water treatment”. CORFO 13CEI2-21803 (Stage-II). (Researcher & Chemistry Advisor)
  • 2017: Grant from the Corporación de Fomento de la Producción (Corfo), title: “CuO-Distillation Membranes Nanocomposites” CORFO 13CEI2-21803 (Stage-I). (Chemistry Advisor)
 
Otros Internacionales:
  • 2019: Grant from the European Program, H-2020, (SFERA-III), “Performance of superhydrophobic NPs-PVDF/Non-Woven Polyester composite membrane in membrane distillation technique” SURPF1904050075, Main Researcher, Fraunhofer-ISE, Freiburg, Germany,
  • 2011: Grant from the Deuscher Akademischer Austausch Dienst (DAAD). Title: “Synthesis, Immobilization, Electrochemistry and Characterization of ruthenium(II) Metalloporphyrinoids for Catalysis, Sensoring and Light Induced Electron Transfer” Referat. DAAD-414. (main researcher)
  • 2007-2010: Grant from the Deutsche Forschungsgemeinschaft (DFG-21316041) “Synthesis, Immobilization and Electrochemical Characterization of Metalloporphyrinoids for Catalysis, Sensoring and Light Induced Electron Transfer” (researcher).
Congresos: 
  • International Workshop on Lithium Industrial Minerals and Energy, December 12-14, 2022, b-cyclodextrin-acrylic acid and adamantane-acrylic acid copolymers as potential supramolecular complementary binders for the self-healing of silicon anodes in Li-Ion. (Poster Presentation)
  • XXXIII-Jornadas Chilenas de Química, January 7-10, 2020, “Membranas superhidrofóbicas compuestas de fluoruro de polivinilideno con nanopartículas de CuO para la destilación de agua por membrana” (Poster Presentation)
  • IX-Coloquio de Macromoléculas Chile-2018, December 5-8, 2018, “Films adhesivos basados en biopolímeros con un derivado de catecol con potencial aplicación en Ingeniería de Tejidos Biológicos” (Poster Presentation)
  • IX-Coloquio de Macromoléculas Chile-2018, December 5-8, 2018, “Películas estimulo-respuesta con propiedades opticas basadas en copolímero de bloques” (Poster Presentation)
  • 4 th. International Conference on Materials Science, October 16-19, 2017, “Uses of a crosslinked -cyclodextrin-epichlorohydrin polymer in the preparation of gold and silver nanoparticles” (oral presentation)
  • VIII Escuela de NanoEstructuras, January 10-13 th , 2017 “-cyclodextrin-epichlorohydrin crosslinked polymer: A versatile scaffold toward biomedical application of nanoparticles containing metals”. Invited Speaker
  • 10 th Workshop on Computational Chemistry and Molecular Spectroscopy (WCCMS), October 17-20 th , 2016 “Inclusion complexes of some potential anticancer drugs in a crosslinked cyclodextrin-epichlorohydrin polymer. (Poster)
  • 3 th. International Conference on Materials Science, October 21-24, 2015, “Crosslinked polymer of -cyclodextrin-epichlorohydrin as capping agent for nanoparticles containing metals” (oral presentation)
  • "QUIMICUBA-2012; VIII Congreso Internacional de Química, octubre 9-12, 2012. “Synthesis and self-assembled on gold of deuteroporphyrinruthenium(II) derivative employing lipoic acid as spacerarm” (poster)
  • IV Internacional de Seminar on Nanosciences y Nanotechnology, Septiembre 17-21, 2012. “Self-assembled of Ruthenium(II)-deuteroporphyrindimethyl ester complexes on gold electrode”. (oral presentation)
  • VI Seminarios de Estudios Avanzados de Diseño Molecular y Bioinformática (SEADIMB), August, 2009, Varadero, Cuba. “Self-Assembling monolayer of ruthenium(II)-(deuteroporphyrin-IX) complexes on gold electrodes as Nitric Oxide detector”(poster).
  • 27 th Latin American Congress on Chemistry and 6 th International Congress on Chemistry and Chemical Engineering, October 16-20, 2006, Ciudad de La Habana, Cuba. “Self-Assembling of ruthenium(II) porphyrinoids complexes on gold electrodes” (poster)
  • 2 st British- Cuban Workshop on Nanoscience and Life Science, November 9-12, 2004, Ciudad de La Habana, Cuba (participant).
  • III Simposio de Fotobiología, Fotofísica y Fotoquímica Universidad de La Habana, March 14-19, 2005, Ciudad de la Habana, Cuba (participant).
  • 3er . Sta Maria Workshop in Bioinorganic Chemistry. July 2005, Habana, Cuba. “Studies of inclusión complexes of Naproxen and Ibuprofen in Soluble Epichlorohydrin--cyclodextrin Polymer”(poster)
Email: 
luis.lemus@usach.cl
Teléfono: 
227 181 052

Abstract

Our research focuses on the synthesis and structural study of new transition metal compounds, mainly Cu, Fe, Ru and Zn. Bimetallic complexes are of particular interest, given the electronic communication that may exist between metal centers and their effect on their photophysical properties.

A family of supramolecular polymetallic complexes are helicates, where the folding of the ligands around the metal centers defines a helical axis, giving these molecules an intrinsic chirality. From the structural point of view, the chiral resolution of helicates and the study of racemization mechanisms in enantiomerically pure complexes are topics studied in our research group.

In addition, helicates are able to bind to DNA strands through specific non-covalent interactions, modifying its structure. In this subject, our interest has been to study the effect of the chirality of helicates on molecular recognition processes and enantioselective binding to DNA.

Línea(s) de investigación: 
Synthesis of coordination compounds. Supramolecular chemistry. DNA recognition through non-covalent interactions with metal complexes.
Jerarquía: 
Asociado
Grados académicos /educación: 
Doctor en Química, Universidad de Santiago de Chile, 2009 |
Licenciado en Química, Universidad de Santiago de Chile, 2004.
Publicaciones: 
  1.  P. Arce, C. Vera, D. Escudero, J. Guerrero, A. Lappin, A. Oliver, D. Jara, G. Ferraudi, L. Lemus.“Structural diversity in Cu(I) complexes of the PNP ligand: From pincer to binuclear coordination modes and their effects upon the electrochemical and photophysical properties”. Dalton Trans., 2017, 46, 13432-13445.
  2. A. Romo, D. Abreu, T. de Paulo, M. Carepo, E. Sousa, L. Lemus, C. Aliaga, A. Batista, O. Nascimento, H. Abruña, I. Diógenes. “Hydroxyl Radical Generation and DNA Nuclease Activity: A Mechanistic Study Based on a Surface- Immobilized Copper Thioether Clip-Phen Derivative” Chem. Eur. J., 2016, 22, 1 – 10.
  3. S. Espinoza, P. Arce, E. San-Martín, L. Lemus, J. Costamagna, L. Farías, M. Rossi, F. Caruso, J. Guerrero.“The Crystal Structure of Mono- and Di-nuclear Copper(I) Complexes with Substituted Triphenylphosphine Ligands”. Polyhedron, 2015, 85, 405–411.
  4. L. Lemus, J. Guerrero, J. Costamagna, R. Lorca, D. Jara, G. Ferraudi, A. Oliver,  G. Lappin. “Resolution and characterization of helicate dimer and trimer complexes of 1,3-bis(9-methyl-1,10- phenanthrolin-2-yl)propane with copper(I)” Dalton Trans., 2013, 42, 11426-11435.
  5. L. Lemus, G. Ferraudi, A. Graham Lappin. “A single- and double-flash flash photolysis study of the sequential biphotonic photoprocesses of Cu(I) phenanthrolines. Comparison of the helicate complex, [Cu2(1,3-bis(9-methyl-1,10-phenanthrolin-2-yl)- propane)2]2+, and [Cu(2,9-dimethyl-1,10- phenanthroline)2]+ photoprocesses” Dalton Trans. 2013, 42, 8637-8643.
  6. M. Escobar, D. Jara, R. Tapia, L. Lemus, R. Fröhlich, J. Guerrero, R. Rojas “Copper(I) complexes bases on a new indazol-4,7-dione ligand” Polyhedron, 2013, 62, 66-74.
  7. D. Jara, L. Lemus, L. Farías, E. Freire, R. Baggio, J. Guerrero.
 “Spectroscopic Evidence in Solid and Solution of a Discrete Copper(I) Tetrahedral Complex Dimer Supported by Supramolecular Interactions”. Eur. J. Inorg. Chem. 2012, 1579-1583.
  8. L. Lemus, J. Guerrero, J. Costamagna, G. Estiú, G. Ferraudi, A. Graham Lappin, A. Oliver and B. C. Noll. “Unfolding of the [Cu2(1,3-bis(9-methyl-1,10-phenanthrolin-2-yl)propane)2]2+ Helicate. Coupling of the Chlorocarbon Dehalogenation to the Unfolding Process”  Inorg. Chem. 2010, 49 (9), 4023–4035.
  9. J. Guerrero, L. Cortez, L. Lemus, L. Farías, J. Costamagna, C. Pettinari, M. Rossi, F. Caruso. “Spectroscopic and electrochemical properties of heteroleptic cationic copper complexes bis-(diphenylphosphino)alkane-(2,2′-biquinoline)copper(I). Crystal structure of bis(diphenylphosphino)ethane-(2,2′-biquinoline)copper(I) perchlorate”. Inorg. Chim. Acta, 2010, 363 (14), 3809-3816.
  10. J. Guerrero, L. Farías, L. Lemus, A. Quintanilla, A. Mena, L. Cortez, R. Baggio, M. Garland “The new Ru(NBD)Cl2(substituted-2,2′-biquinoline) complexes. Synthesis and characterization”. Polyhedron, 2006, 25, 9–16.
Investigaciones : 

“Helicates as DNA Binders”. Fondecyt de Iniciación en Investigación 11130172.

Email: 
carla.toledo@usach.cl
Teléfono: 
227 181 080

Abstract:

Prof. Carla Toledo, joined the Chemistry and Biology Faculty in January 2017. Her research on Analytical chemistry is focused on chromatographic separation science and green sample preparation. She is specifically interested in employing of green  solvents as ionic liquids (ILs), switchable solvents (SS), and Deep Eutectic Solvents (DES) particularly in microextraction techniques for the determination of emerging contaminants concern and other organic pollutants from food and/or  environmental matrices. Currently she supervises the Chromatographic Analysis and Green Analytical Chemistry Laboratory (LACQAV)
Línea(s) de investigación: 
Chromatographic Techniques, Sample preparation, Green Analytical Chemistry .
Jerarquía: 
Asistente
Grados académicos /educación: 
Doctora en Química (2012), Universidad de Chile
Licenciada en Ciencias Ambientales m/Química (2006), Universidad de Chile
Químico Ambiental (2006), Universidad de Chile
Publicaciones: 
  1. K.C. Conceicao, C.A. Villamar-Ayala*, A. Plaza-Garrido, C. Toledo-Neira. Seasonal behavior of pharmaceuticals and personal care products within Chilean rural WWTPs under COVID-19 pandemic conditions. Journal of Environmental Chemical Engineering. (2023) 11 (5) 110984.
  2. S. Piña, P. Sepúlveda, A. García-García, A. Moreno- Bárcenas, C. Toledo-Neira, R. Salazar*. Fast simultaneous electrochemical detection of Bisphenol-A and Bisphenol-S in urban wastewater using a graphene oxide-iron nanoparticles hybrid  sensor. Analytica Chimica Acta (2023) 468, 143164.
  3. A. Mesías-Salazar, K. Rebolledo-Robles, R. Salazar, M. A. Bravo, R. Lucena, C. Toledo-Neira*. Hydrophobic Deep Eutectic Solvent as extractant phase for determination of six carcinogenic Polycyclic Aromatic Hydrocarbons in Tea and Coffee infusion samples. Microchemical Journal (2023) 193, 109022.
  4. C. Rivera-Vera, D. Muñoz-Lira, M. Aranda, C. Toledo-Neira, R. Salazar*. Study of degradation of norfloxacin antibiotic and their intermediates by natural solar photolysis. Environmental Science and Pollution Research (2023) 30, 41014-41027.
  5. S. Campos, J. Lorca, J. Vidal, W. Calzadilla, C. Toledo-Neira, M. Aranda, S. Miralles- Cuevas, A. Cabrera-Reina, R. Salazar*. Removal of contaminants of emerging concern by solar photo electro-Fenton process in a solar electrochemical raceway pond reactor. Process safety and environmental protection, (2023) 169, 660-670.
  6. S. Bugueño-Carrasco, H. Monteil, C. Toledo-Neira, M.A. Sandoval, A.Thiam, R. Salazar*. Elimination of pharmaceutical pollutants by solar photoelectro-Fenton process in a pilot plant. Environmental Science and Pollution Research, (2020)
  7. G. Lasarte-Aragonés, A. Álvarez-Lueje, R. Salazar, C. Toledo-Neira*. Application of Switchable Hydrophobicity Solvents for Extraction of Emerging Contaminants in Wastewater Samples. Molecules (2020) 25, 86 (1-12).
  8. J. Ríos-Gómez, M.T. García-Valverde, A.I. López-Lorente, C. Toledo-Neira, R. Lucena, S. Cárdenas. Polymeric ionic liquid immobilized onto paper as sorptive phase in microextraction Anal. Chim. Acta (2020) 1094, 47-56.
  9. C. Rivera-Vera, G. Lasarte-Aragonés, M. A. Bravo, D. Muñoz-Lira, R. Salazar, C. Toledo-Neira. Ionic liquids-based dispersive liquid-liquid microextraction for determination of carcinogenic polycyclic aromatic hydrocarbons in tea beverages: Evaluation of infusion preparation on pollutants release, Food Control (2019) 106, 106685.
  10. A. Osorio, C. Toledo-Neira, M. A. Bravo. Critical evaluation of third-order advantage with highly overlapped spectral signals. Determination of fuoroquinolones in fish-farming waters by fuorescence spectroscopy coupled to multivariate calibration, Talanta (2019) 204, 438-445.
  11. P. Sierra-Rosales, C. Toledo-Neira, P. Ortuzar-Salazar, J.A. Squella. MWCNT-modified Electrode for Voltammetric Determination of Allura Red and Brilliant Blue FCF in Isotonic Sport Drinks, Electroanalytica (2019) 31, 1-9.
  12. C. Candia-Onfray, N. Espinoza, E.B. Sabino da Silva, C. Toledo-Neira, L.C. Espinoza, R. Santander, V. García, R. Salazar. Treatment of winery wastewater by anodic oxidation using BDD electrode, Chemosphere (2018) 206, 709-717. 
  13. C. Toledo-Neira, M.A. Bravo, A. Álvarez-Lueje, New approach for determination of flumequine and oxolinic acid in aqueous samples by Ionic liquid-based dispersive liquid-liquid microextraction and high-performance liquid chromatography–fluorescence detection J. Chil. Chem. Soc. (2016) 61 (4) 3262-3266.
  14. P. Sierra-Rosales, C. Toledo‑Neira, J. Arturo Squella, Electrochemical determination of food colourants in soft drinks using MWCNT modified GCE. Sens. Act B. (2017) 1257-1264.
  15. C. Toledo-Neira, A. Álvarez-Lueje, Ionics liquids for improving the extraction of NSAIDs in water samples using dispersive liquid-liquid microextraction by high performance liquid chromatography-diode array-fluorescence detection, Talanta 134 (2015) 619-626.
  16. M. S. Mariotti, C. Toledo, K. Hevia, J.P. Gómez, A. Fromberg, K. Granby, J. Rosowski,  O. Castillo, F. Pedreschi, Are the Chilean exposed to dietary furan?, Food Addit. Contam. 10 (2013) 1715-1721.
  17. C. Toledo-Neira, P. Enríquez, P. Richter, Integrated pressurized solvent extraction - cleanup for the rapid determination of polychlorinated biphenyls in meat samples. J. Braz. Chem. Soc. 24 (2012) 743-748.
  18. C. Toledo-Neira, P. Richter, Rapid Methods in Analytical Chemistry – Review, Anal. Letters 45 (2012) 949-967.
  19. M. Préndez, C. Barra, C. Toledo, P. Richter. Alkanes and Polycyclic Aromatic Hydrocarbons in Marine Surficial Sediment Near Antarctic Stations at Fildes Peninsula, King George Island, Antarct. Science 23 (2011) 578-588.
  20. C.  Toledo,  P.  Enríquez, M.  Garrido, B.  Fernández-Band,  P. Richter, Headspace-mass spectrometry with alternative chromatography separation using a column Switching System for the Screening and Determination of BTEX and Styrene in Comestible Oil  Anal. Letters. 43 (2010) 843-850.
  21. Rocco G, C. Toledo, I. Ahumada, B. Sepúlveda, A. Cañete, P. Richter, Determination  of Polychlorinated Biphenyls in Biosolids using Continuous Ultrasound-Assisted Pressurized Solvent Extraction and Gas Chromatography – Mass Spectrometry, J. Chromatogr. A, 1193 (2008) 32-36.
  22. C. Toledo, L. Valle, J. Narváez, P. Richter, Screening Method for Rapid Determination of Polychlorinated Biphenyls in Transformer Oil, J. Braz. Chem. Soc. 18 (2007) 937-942.
  23. P. Richter, M.I. Toral, C. Toledo, Subcritical Water Extraction and Determination of Nifedipine in Pharmaceutical Formulations, J. AOAC Int. 89 (2006) 365-368.
Premios y Honores: 
  1. Presidenta de la División de Química Analítica y Ambiental de Chile 2022-2024.
  2. Beca iberoamericana de jóvenes profesores e investigadores 2017. Programa de apoyo a la educación superior Santander Universidades. 2017.
  3. Pasantía doctoral. Programa BECAS CHILE. 2009
  4. Apoyo de tesis. Programa CONICYT. 2009
  5. Mejor trabajo científico, Jornadas de Investigación, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile. 2006
Investigaciones : 

Investigaciones que realizó o está realizando

  • Entrenamiento “Determinación de acrilamida en alimentos mediante GC/MS-EI”. Instituto de Investigación de Alimentos (VÝSKUMNÝ ÚSTAV POTRAVINÁRSKY), Centro Nacional de Alimento y Agricultura a cargo de la Dra. Zuzana Ciesarovà, Bratislava, Eslovaquia. 2012
  • Estancia doctoral  “Microextracción  líquida  dispersiva  basada  en  el  empleo  de  líquidos iónicos  para la determinación de bifenilos policlorados en carnes de pollo mediante cromatografía de gases/espectrometría de masas”. Grupo de investigación en automatización, miniaturización y calidad de procesos de medida química y bioquímica, dirigido por el Dr. Miguel Valcárcel. Facultad de Química. Universidad de Córdoba. España 2010
Proyectos: 
  • 2022 – 2026: Proyecto Fondecyt Regular 12200459 (Co-Investigadora) “Dimers and heterodimers of tryptophan and tyrosine as biomarkers of protein oxidation: analytical approaches for their quantification in isolated proteins, cell extracts and C.elegans worms”. Universidad de Santiago de Chile.
  • 2022 – 2026: Proyecto Fondecyt Regular 1220077(Co-Investigadora) “New development of a solar photo-electrochemical raceway pond reactor for the elimination of micropollutants by solar photoelectro_Fenton process”. Universidad de
    Santiago de Chile.
  • 2022 – 2024: Proyecto DICYT ASOCIATIVO 022242TN_DAS (Inv. Principal) “Presencia y concentración de contaminantes emergentes y material microbiológico en aguas residuales: estudio geográfico y temporal”. Universidad de Santiago de Chile.
  • 2022 – 2023: Proyecto DICYT POSTDOCTORADO 022142TN (Inv. Principal) “Desarrollo de una metodología electroquímica para el análisis simultaneo de Bisfenol A y Bisfenol S en aguas residuales”. Universidad de Santiago de Chile.
  • 2021 – 2022: Proyecto DICYT POSTDOCTORADO 122042_TN (Inv. Principal) “Uso de Solventes Eutécticos Profundos (DES) para la determinación de Hidrocarburos Aromáticos Policíclicos (PAHs) en muestras de té mediante cromatografía liquida de ultra
    eficiencia”. Universidad de Santiago de Chile.
  • 2020 – 2024: Proyecto Fondecyt Regular 1201978 (Inv. Principal). “Use of non-conventional solvents for determination of carcinogenic polycyclic aromatic hydrocarbons in tea and herbal infusions”. Universidad de Santiago de Chile.
    2016 – 2019:  Proyecto de Inserción a la Academia PAI79160152 (Inv. Principal). “Fortalecimiento de la Docencia e Investigación en el área de Química Analítica: uso de solventes verdes en el contexto de la microextracción”. Universidad de Santiago de Chile.
  • 2016 – 2019:  Proyecto Fondecyt iniciacion  11160835 (Inv. Principal).“Use of Ionic Liquids and switchable solvents as green solvents in microextraction”. Universidad de Santiago de Chile.
  • 2013 – 2016: Proyecto Postdoctorado Nacional 3140459 (Inv. Principal). “Liquidos ionicos como disolventes verdes de ultima generación para la determinacion de contaminantes emregentes en muestras acuosas”. Universidad de Chile. 
Otras actividades relevantes: 
  • Secretaria División de Química analítica de Chile. 2018-2020.
  • Miembro Sociedad Chilena de Química y  División de Química Analítica
  • Miembro comité científico del XIII Encuentro de Química Analítica y Ambiental 2016.

  • Revisora del Journal of the Chilean Chemical Society, Current Analytical Chemistry, Chimica Select.

Congresos: 
  • Ionic liquids-based dispersive liquid-liquid microextraction for determination of carcinogenic polycyclic aromatic hydrocarbons in tea beverages: Evaluation of infusion preparation on pollutants reléase. C. Toledo-Neira, C. Rivera-Vera, G.Lasarte-Aragonés. 4th ILSEPT 2019, Sitges, Spain.
  • Analytical approach for determination of PAHs in tea infusion using ionic liquids as extraction solvent. C. Toledo-Neira, D. Muñoz-Lira, C. Rivera-Vera, R. Salazar. 7th EuCheMS Chemistry congress. August 2018, Liverpool, UK.
  • Detection of emerging contaminants in water samples by Homogeneous Liquid-Liquid Microextraction using switchable hidrophilicity solvents as acceptor phase. C. Rivera-Vera, C. Toledo-Neira, G. Lasarte-Aragonés. 10th International Conference on Instrumental Methods of Analysis: Modern Trends and Applications. September 2017, Heraklion, Greece.
  • New approach for determination of NSAIDs in urine sample by Ionic liquid-based dispersive liquid-liquid microextraction. C. Toledo-Neira, C. Rivera-Vera, C. Lingue. EUROANALYSIS, august 2017, Stockolm, Sweden.
  • Detección de hormonas esteroidales en muestras de agua mediante microextracción liquida-liquida homogénea con disolventes conmutables como fase aceptora. Carla Toledo-Neira, Guillermo Lasarte-Aragonés, Alejandro Álvarez-Lueje. VI Congreso Iberoamericano de Química Analítica y Encuentro Nacional de Química Ambiental. Noviembre 2016, Cancún, México.
  • Uso de herramientas quimiométricas en la determinación de flumequina y acido oxolínico mediante microextracción liquido-liquido dispersiva utilizando liquidos iónicos. C. Toledo-Neira, M. Bravo, A. Álvarez-Lueje - 32º Congreso Latinoamericano de Química y XXXI Jornadas chilenas de Química, Enero 2016, Concepción, Chile.
  • Detección electroquímica de colorantes alimenticios con electrodos modificados con nanotubos de carbono. P. Cañete-Rosales, C. Toledo, J.A. Squella - 32º Congreso Latinoamericano de Química y XXXI Jornadas chilenas de Química, Enero 2016, Concepción, Chile.
  • Ionics liquids for improving the extraction of NSAIDs in water samples using dispersive liquid liquid microextraction by high pressure liquid chromatography-diode array detection. C. Toledo-Neira, A. Álvarez-Lueje - EUROANALYSIS, September 2015, Bordeaux, France.
  • Líquidos iónicos en microextracción liquida-liquida dispersiva para la determinación de antiinflamatorios en muestras de aguas. C. Toledo-Neira, A. Álvarez-Lueje - VII Congreso Iberoamericano de Física  y Química Ambiental - XII Encuentro de Química  Analítica y Ambiental, Octubre 2014, Viña del Mar, Chile.
  • Optimización de un sistema de extracción con solvente acelerado (ASE) para la determinación  de  bifenilos  policlorados  (PCBs)  en  carnes  de  cerdo  y pollo.  C. Toledo, C. Smelt, P. Enríquez, P. Richter - XV  Encuentro  Nacional  de  Química  Analítica  y  III  Congreso  Iberoamericano  de Química Analítica. Octubre 2009, Salvador de Bahía, Brasil.
  • Screening rápido y confirmación de compuestos orgánicos volátiles halogenados en aguas residuales a través de un sistema alternativo HS-MS y HS-GC-MS. C. Toledo y P. Richter - II  Congreso  Iberoamericano  y  IV  Argentino  de  Química  Analítica.  Agosto  2007, Buenos Aires, Argentina.
  • Determinación  de  Hidrocarburos  Aromáticos  Policíclicos  (PAHs)  y  de  Bifenilos Policlorados   (PCBs)  en  biosólidos  utilizando  disolventes  presurizados  para  la extracción y GC - MS para su cuantificación. M. Retamal, G. Rocco, C. Toledo, A. Maricán, I. Ahumada y P. Richter - II  Congreso  Iberoamericano  y  IV  Argentino  de  Química  Analítica.  Agosto  2007, Buenos Aires, Argentina.
  • Screening y confirmación de compuestos orgánicos volátiles utilizando espectrometría  de  masas  sin  y  con  acoplamiento  a  cromatografía  gaseosa. P. Richter, C. Toledo - XI Congreso Latinoamericano de Cromatografía  y Ciencias Afines. Junio 2006, Mérida, México.

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